You handle the pressure and stress of running a business by practicing self-care. Take time to care for yourself by engaging in activities that you enjoy and help you relax. This can include exercise, reading, or spending time with loved ones. You also need to set boundaries. Establish boundaries between your work and personal life. This means setting aside time for yourself and your loved ones and not letting work interfere with that time. Then always take break. Taking regular breaks throughout the day can help you recharge and refocus. Running a business can be a lot of work, so delegate tasks to others who can help share the load.